Studies of Plant Mechanisms in Elipulse Capsules
Discussion: Plant composition mechanism of Elipulse
Main components of Elipulse are ginseng (red ginseng), cassia twig and ligusticum wallichii.
Red ginseng contains panaxoside, ginseng essence, ginseng ene, fatty acid, essential oil, vitamin(e), enzyme, etc. Ginsenoside is the material basis of the ginseng biological activity, which has non-specific resistance ability against all kinds of physical, chemical and biological harmful stimuluses and recovers the disordered functions. Red ginseng can enhance the body's immune function, having stimulative effects on both humoral immunity and cell-mediated immunity and also strengthen the phagocytic function of reticuloendothelial system (RES). It can improve the myocardial contraction force. During the heart failure, the cardiac effect of red ginseng is much more notable [3]. Total ginsenoside ginseng root is resistant to ischemia and can increase myocardial hypoxia tolerance ability. Research finds that total ginsenoside ginseng root can prevent hydroxyl radical from damaging cardiac muscle cells, improve myocardial cell survival rate and reduce myocardial apoptosis percentage.
Cassia twig contains volatile oil which mainly are cassia oil, cinnamaldehyde and cinnamyl acetate.
Cassia oil can strengthen the heart and has the function of diuretic effect; Cinnamic aldehyde can dilate skin blood vessels, stimulate the secretion of sweat gland and has the antipyretic effect; cassia twig not only can dilate blood vessels, increase coronary blood flow[4], but also has the stronger analgesia and sedation effect.
Ligusticum wallichii contains Z-Ligustilide, ligustilide, ligustrazine, organic acids (such as ferulic acid), vitamin A and cane sugar, etc. Blood components are mainly ligustrazine and ferulic acid[5]. Ligustrazine is a kind of new calcium ion antagonist having pharmacological activities[6] of inhibiting free radicals, improving endogenous superoxide dismutase (SOD) activity, eliminating oxygen free radicals, improving blood rheology, inhibiting of platelet aggregation, inhibiting fibrosis, regulating lipid metabolism, anti-lipid peroxidation and vascular dilation,etc. Ferulic acid can dilate coronary artery, increase coronary blood flow, reduce the myocardial oxygen consumption, inhibit the platelet aggregation. It has disaggregation effect on clotted platelets and pharmacologic action of reducing the platelet surface activity,etc.; ferulic acid can also reduce the serum total cholesterol of high fat rats, high-density lipoprotein cholesterol levels,etc.[7]